Publications

• CBSGI policy is to accelerate research by making pre-prints of all manuscripts publicly available.

• CBSGI authors denoted in bold

Comparative analysis reveals a role of TGF-β in shaping the residency-related transcriptional signature in tissue-resident memory CD8+ T cells
Nath AP*, Braun A*, Ritchie SC, Carbone FR, MacKay L, Gebhardt T*, Inouye M*.
PLoS ONE 2019. 14(2): e0210495.

Genomic risk prediction of coronary artery disease in 480,000 adults: Implications for primary prevention
Inouye M*, Abraham G*, Nelson CP, Wood AM, Sweeting MJ, Dudbridge F, Lai FY, Kaptoge S, Brozynska M, Wang T, Ye S, Webb TR, Rutter MK, Tzoulaki I, Patel RS, Loos RJF, Keavney B, Hemingway H, Thompson J, Watkins H, Deloukas P, Di Angelantonio E, Butterworth AS, Danesh J, Samani NJ* for The UK Biobank CardioMetabolic Consortium CHD Working Group
Journal of the American College of Cardiology 2018. 72(16):1883-93.    pre-print    metaGRS

Trajectories of childhood immune development and respiratory health relevant to asthma and allergy
Tang HHF, Teo SM, Belgrave DCM, Evans MD, Jackson DJ, Brozynska M, Kusel MMH, Johnston SL, Gern JE, Lemanske RF, Simpson A, Custovic A, Sly PD, Holt PG, Holt KE, Inouye M
eLife 2018. 7:e35856.    pre-print

Biomarker glycoprotein acetyls is associated with the risk of a wide spectrum of incident diseases and stratifies mortality risk in angiography patients
Kettunen J*, Ritchie SC*, Anufrieva O, Lyytikainen LP, Hernesniemi J, Karhunen PJ, Kuukasjarvi P, Laurikka J, Kahonen M, Lehtimaki T, Havulinna A, Salomaa V, Mannisto S, Ala-Korpela M, Perola M, Inouye M*, Wurtz P*
Circulation: Genomic and Precision Medicine 2018. 11:e002234.    pre-print

Power, false discovery rate and Winner’s Curse in eQTL studies
Huang QQ, Ritchie SC, Brozynska M, Inouye M.
Nucleic Acids Research 2018. gky780.    pre-print

Identification of expression quantitative trait loci associated with schizophrenia and affective disorders in normal brain tissue
Bhalala OG, Nath AP, UK Brain Expression Consortium, Inouye M, Sibley CR
PLOS Genetics 2018. 14(8):e1007607.    pre-print

Airway microbiota dynamics identify a critical window for interplay of pathogenic bacteria and allergy in childhood respiratory disease
Teo SM, Tang HHF, Mok D, Judd LM, Watts SC, Pham K, Holt BJ, Kusel M, Serralha M, Troy N, Bochkov YA, Grindle K, Lemanske RM, Johnston SL, Gern JE, Sly PD, Holt PG, Holt KE*, Inouye M*
Cell Host & Microbe 2018. 24(3):341-352.    pre-print

FastSpar: Rapid and scalable correlation estimation for compositional data
Watts SC, Ritchie SC, Inouye M, Holt KE
Bioinformatics 2018. bty734.    pre-print

Frequent transmission of the Mycobacterium tuberculosis Beijing lineage and positive selection for the EsxW Beijing variant in Vietnam
Holt KE, McAdam P, Phan VKT, Nguyen TTT, Dang TMH, Nguyen NL, Nguyen HL, Nguyen TQN, Hoang TH, Vu TNH, Thwaites G, Edwards DJ, Nath AP, Pham K, Ascher DB, Farrar JJ, Khor CC, Teo YY, Inouye M, Caws M, Dunstan SJ.
Nature Genetics 2018. 50:849–856.    pre-print

Pre-prints on BioRxiv:

Multivariate genome-wide association analysis of a cytokine network reveals variants with widespread immune, haematological and cardiometabolic pleiotropy
Nath AP, Ritchie SC, Grinberg NF, Tang HHF, Huang QQ, Teo SM, Ahola-Olli AV, Würtz P, Havulinna AS, Aalto K, Pitkänen N, Lehtimäki T, Kähönen M, Lyytikäinen LP, Raitoharju E, Seppälä I, Sarin AP, Ripatti S, Palotie A, Perola M, Viikari JS, Jalkanen S, Maksimow M, Salmi M, Wallace C, , Raitakari OT, Salomaa V, Abraham G, Kettunen J, Inouye M

Elevated alpha-1 antitrypsin is a major component of GlycA-associated risk for future morbidity and mortality
Ritchie SC, Kettunen J, Brozynska M, Nath AP, Havulinna, Mannisto S, Perola M, Salomaa V, Ala-Korpela M, Abraham G, Wurtz P, Inouye M

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